Version 5.4
Homo sapiens Gene: SYNRG
Summary
InnateDB Gene IDBG-777569.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNRG
Gene Name synergin, gamma
Synonyms AP1GBP1; SYNG
Species Homo sapiens
Ensembl Gene ENSG00000275066
Encoded Proteins
IDBP-813215
synergin, gamma
IDBP-813219
synergin, gamma
IDBP-813221
synergin, gamma
IDBP-813224
synergin, gamma
IDBP-813225
synergin, gamma
IDBP-813226
synergin, gamma
IDBP-813229
synergin, gamma
IDBP-813233
synergin, gamma
IDBP-813235
synergin, gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:37514797-37609496
Strand Reverse strand
Band q12
Transcripts
ENST00000612223 ENSP00000483453
ENST00000612641
ENST00000621136 ENSP00000484529
ENST00000616179 ENSP00000482962
ENST00000614941 ENSP00000481151
ENST00000619541 ENSP00000477885
ENST00000622045 ENSP00000483063
ENST00000619914
ENST00000614196 ENSP00000482858
ENST00000618829
ENST00000611910
ENST00000621605
ENST00000614000
ENST00000619976
ENST00000612770 ENSP00000480047
ENST00000620424 ENSP00000482631
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0030121 AP-1 adaptor complex
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882
HUGO
OMIM
CCDS CCDS11321 CCDS11322 CCDS54113 CCDS54114 CCDS59284 CCDS59285
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca