Version 5.4
Homo sapiens Gene: PIGW
Summary
InnateDB Gene IDBG-773592.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGW
Gene Name phosphatidylinositol glycan anchor biosynthesis, class W
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000277161
Encoded Proteins
IDBP-808052
phosphatidylinositol glycan anchor biosynthesis, class W
IDBP-808057
phosphatidylinositol glycan anchor biosynthesis, class W
IDBP-808061
phosphatidylinositol glycan anchor biosynthesis, class W
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:36535020-36539310
Strand Forward strand
Band q12
Transcripts
ENST00000619326 ENSP00000480475
ENST00000614443 ENSP00000482202
ENST00000620233 ENSP00000480021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006501 C-terminal protein lipidation
GO:0006506 GPI anchor biosynthetic process
GO:0016254 preassembly of GPI anchor in ER membrane
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_952
Synthesis of glycosylphosphatidylinositol (GPI) pathway
REACT_1853
Post-translational modification: synthesis of GPI-anchored proteins pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q7Z7B1
TrEMBL C9JLC8
UniProt Splice Variant
Entrez Gene 284098
UniGene
RefSeq NM_178517 XM_005257238 XM_006721831 XM_006725317 XM_006725318
HUGO HGNC:23213
OMIM 610275
CCDS CCDS11313
HPRD
IMGT
EMBL AB097818 AC126327 AK094752
GenPept BAC04413 BAC77021
RNA Seq Atlas 284098

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca