Version 5.4
Bos taurus Gene: TTYH1
Summary
InnateDB Gene IDBG-642055.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TTYH1
Gene Name protein tweety homolog 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003470
Encoded Proteins
IDBP-694472
protein tweety homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167614:
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63090945-63104304
Strand Forward strand
Band
Transcripts
ENSBTAT00000004515 ENSBTAP00000004515
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005254 chloride channel activity
GO:0005509 calcium ion binding
GO:0072320 volume-sensitive chloride channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0007067 mitotic nuclear division
GO:0016337 single organismal cell-cell adhesion
GO:0031589 cell-substrate adhesion
GO:0044070 regulation of anion transport
GO:0046847 filopodium assembly
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030868 smooth endoplasmic reticulum membrane
GO:0031527 filopodium membrane
GO:0032433 filopodium tip
GO:0034707 chloride channel complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000167614
View Gene Order
ENSMUSG00000030428
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N0P0
UniProt Splice Variant
Entrez Gene 767943
UniGene Bt.7619
RefSeq NM_001077015
HUGO HGNC:13476
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047779
GenPept
RNA Seq Atlas 767943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca