Version 5.4
| Bos taurus Gene: EDEM3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-637333.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | EDEM3 | ||||||||
| Gene Name | ER degradation-enhancing alpha-mannosidase-like 3 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000019264 | ||||||||
| Encoded Proteins |
ER degradation enhancer, mannosidase alpha-like 3
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116406:
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 16:67209942-67278874 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
ER Quality Control Compartment (ERQC) pathway
Calnexin/calreticulin cycle pathway
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
ER Quality Control Compartment (ERQC) pathway
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
Calnexin/calreticulin cycle pathway
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| KEGG |
Protein processing in endoplasmic reticulum pathway
Protein processing in endoplasmic reticulum pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1B789 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 519058 | ||||||||
| UniGene | Bt.60535 | ||||||||
| RefSeq | NM_001205853 | ||||||||
| HUGO | HGNC:16787 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02043595 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 519058 | ||||||||