Version 5.4
Bos taurus Gene: CALCA
Summary
InnateDB Gene IDBG-632774.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CALCA
Gene Name Calcitonin
Synonyms CALCA
Species Bos taurus
Ensembl Gene ENSBTAG00000047380
Encoded Proteins
IDBP-684424
Calcitonin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:38041580-38044615
Strand Reverse strand
Band
Transcripts
ENSBTAT00000066189 ENSBTAP00000053947
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005179 hormone activity
GO:0005515 protein binding
GO:0031716 calcitonin receptor binding
GO:0042802 identical protein binding
Biological Process
GO:0001984 vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
GO:0002027 regulation of heart rate
GO:0002548 monocyte chemotaxis
GO:0006874 cellular calcium ion homeostasis
GO:0006954 inflammatory response
GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007566 embryo implantation
GO:0007631 feeding behavior
GO:0009408 response to heat
GO:0030279 negative regulation of ossification
GO:0031645 negative regulation of neurological system process
GO:0032147 activation of protein kinase activity
GO:0045762 positive regulation of adenylate cyclase activity
GO:0045776 negative regulation of blood pressure
GO:0045778 positive regulation of ossification
GO:0045779 negative regulation of bone resorption
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045986 negative regulation of smooth muscle contraction
GO:0048265 response to pain
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0030424 axon
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_205369
Signaling by GPCR pathway
REACT_206540
Amyloids pathway
REACT_206547
G alpha (s) signalling events pathway
REACT_214353
Signal Transduction pathway
REACT_214436
GPCR downstream signaling pathway
REACT_220217
GPCR ligand binding pathway
REACT_214352
Calcitonin-like ligand receptors pathway
REACT_207087
Disease pathway
REACT_204109
Class B/2 (Secretin family receptors) pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P01260
TrEMBL B5UBG1
UniProt Splice Variant
Entrez Gene 514876
UniGene Bt.14302
RefSeq NM_001143737
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB462435 DAAA02040622
GenPept BAG72140
RNA Seq Atlas 514876

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca