Version 5.4
Homo sapiens Gene: SELT
Summary
InnateDB Gene IDBG-61227.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SELT
Gene Name selenoprotein T precursor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198843
Encoded Proteins
IDBP-476337
Selenoprotein T
IDBP-480203
Selenoprotein T
IDBP-484661
Selenoprotein T
IDBP-476864
Selenoprotein T
IDBP-475857
Selenoprotein T
IDBP-811735
selenoprotein T precursor
IDBP-811737
selenoprotein T precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:150602875-150630445
Strand Forward strand
Band q25.1
Transcripts
ENST00000480740 ENSP00000417762
ENST00000471696 ENSP00000418910
ENST00000477889 ENSP00000417932
ENST00000492132 ENSP00000417703
ENST00000485923 ENSP00000420390
ENST00000466234
ENST00000619570 ENSP00000478006
ENST00000615547 ENSP00000479292
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008430 selenium binding
Biological Process
GO:0009749 response to glucose
GO:0031016 pancreas development
GO:0035773 insulin secretion involved in cellular response to glucose stimulus
GO:0042593 glucose homeostasis
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005783 endoplasmic reticulum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000075700
View Gene Order
ENSBTAG00000031435
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.369052 Hs.527469 Hs.595376 Hs.610777
RefSeq NM_016275
HUGO
OMIM
CCDS CCDS46936
HPRD 07446
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca