Version 5.4
Mus musculus Gene: Gypc
Summary
InnateDB Gene IDBG-605531.2
Last Modified 2013-04-25 [Report errors or provide feedback]
Gene Symbol Gypc
Gene Name glycophorin C
Synonyms 0610037F22Rik; Cd236r
Species Mus musculus
Ensembl Gene ENSMUSG00000090523
Encoded Proteins
IDBP-621727
glycophorin C
IDBP-621729
glycophorin C
IDBP-621731
glycophorin C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136732:
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:32528322-32560034
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000174459 ENSMUSP00000134317
ENSMUST00000174000 ENSMUSP00000133874
ENSMUST00000172434 ENSMUSP00000128514
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030863 cortical cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136732
View Gene Order
ENSBTAG00000014863
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05144
Malaria pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05144
Malaria pathway
INOH
PID NCI
Cross-References
SwissProt Q78HU7
TrEMBL F7D1I5 G3UXY6
UniProt Splice Variant
Entrez Gene 71683
UniGene Mm.292145 Mm.474823
RefSeq NM_001048207
OMIM
CCDS CCDS57118
HPRD
IMGT
MGI ID MGI:1098566
MGI Symbol Gypc
EMBL AC098881 AY234183 BC027408
GenPept AAH27408 AAP70024
RNA Seq Atlas 71683

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca