Version 5.4
Homo sapiens Gene: SYT7
Summary
InnateDB Gene IDBG-50227.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYT7
Gene Name synaptotagmin VII
Synonyms IPCA-7; IPCA7; PCANAP7; SYT-VII; SYTVII
Species Homo sapiens
Ensembl Gene ENSG00000011347
Encoded Proteins
IDBP-50229
synaptotagmin VII
IDBP-603872
synaptotagmin VII
IDBP-588336
synaptotagmin VII
IDBP-586515
synaptotagmin VII
IDBP-588943
synaptotagmin VII
IDBP-596711
synaptotagmin VII
IDBP-588894
synaptotagmin VII
IDBP-600560
synaptotagmin VII
IDBP-598959
synaptotagmin VII
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:61515313-61581148
Strand Reverse strand
Band q12.2
Transcripts
ENST00000263846 ENSP00000263846
ENST00000540677 ENSP00000444201
ENST00000539246 ENSP00000438171
ENST00000539468 ENSP00000441184
ENST00000539008 ENSP00000439694
ENST00000542836 ENSP00000444568
ENST00000542670 ENSP00000444019
ENST00000535826 ENSP00000437720
ENST00000540831
ENST00000545053 ENSP00000443576
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001778 plasma membrane repair
GO:0006887 exocytosis
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0050796 regulation of insulin secretion
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0031045 dense core granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024743
View Gene Order
ENSBTAG00000019947
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.684589
RefSeq NM_001252065 NM_001300773 NM_004200 XM_005274388
HUGO
OMIM
CCDS CCDS31577 CCDS58139 CCDS73298
HPRD 11965
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca