Version 5.4
Homo sapiens Gene: SCAMP1
Summary
InnateDB Gene IDBG-30586.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAMP1
Gene Name secretory carrier membrane protein 1
Synonyms SCAMP; SCAMP37
Species Homo sapiens
Ensembl Gene ENSG00000085365
Encoded Proteins
IDBP-812778
secretory carrier membrane protein 1
IDBP-812773
secretory carrier membrane protein 1
IDBP-812776
secretory carrier membrane protein 1
IDBP-812764
secretory carrier membrane protein 1
IDBP-812769
secretory carrier membrane protein 1
IDBP-812771
secretory carrier membrane protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:78360583-78479071
Strand Forward strand
Band q14.1
Transcripts
ENST00000320280 ENSP00000478292
ENST00000511551 ENSP00000482491
ENST00000510030 ENSP00000478205
ENST00000506858
ENST00000621999 ENSP00000481022
ENST00000614488 ENSP00000478071
ENST00000618166 ENSP00000480865
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0006887 exocytosis
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006897 endocytosis
GO:0015031 protein transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0016021 integral component of membrane
GO:0030136 clathrin-coated vesicle
GO:0030672 synaptic vesicle membrane
GO:0042589 zymogen granule membrane
GO:0045202 synapse
GO:0055038 recycling endosome membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 9522
UniGene
RefSeq NM_001290229 NM_004866
HUGO HGNC:10563
OMIM 606911
CCDS CCDS75264
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 9522

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca