Version 5.4
Mus musculus Gene: Kcnj16
Summary
InnateDB Gene IDBG-213985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnj16
Gene Name potassium inwardly-rectifying channel, subfamily J, member 16
Synonyms 6430410F18Rik; AI132396; Kir5.1
Species Mus musculus
Ensembl Gene ENSMUSG00000051497
Encoded Proteins
IDBP-268360
potassium inwardly-rectifying channel, subfamily J, member 16
IDBP-268362
potassium inwardly-rectifying channel, subfamily J, member 16
IDBP-538175
potassium inwardly-rectifying channel, subfamily J, member 16
IDBP-533343
potassium inwardly-rectifying channel, subfamily J, member 16
IDBP-716515
IDBP-716330
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153822:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which tends to allow potassium to flow into rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may function in fluid and pH balance regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:110968033-111027968
Strand Forward strand
Band E2
Transcripts
ENSMUST00000106636 ENSMUSP00000102247
ENSMUST00000106635 ENSMUSP00000102246
ENSMUST00000125692 ENSMUSP00000119921
ENSMUST00000150902 ENSMUSP00000121758
ENSMUST00000178798 ENSMUSP00000137414
ENSMUST00000180023 ENSMUSP00000136382
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000153822
View Gene Order
ENSBTAG00000024903
Not yet available
Pathways
NETPATH
REACTOME
REACT_214393
Inwardly rectifying K+ channels pathway
REACT_208267
G protein gated Potassium channels pathway
REACT_203664
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_207065
Activation of GABAB receptors pathway
REACT_202800
Potassium Channels pathway
REACT_217868
GABA B receptor activation pathway
REACT_224131
GABA receptor activation pathway
REACT_199080
Potassium transport channels pathway
REACT_259290
Neuronal System pathway
REACT_226457
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
REACT_233318
Transmission across Chemical Synapses pathway
REACT_208837
Activation of G protein gated Potassium channels pathway
KEGG
mmu04971
Gastric acid secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25004
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
REACT_25031
GABA B receptor activation pathway
REACT_75831
Activation of G protein gated Potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_25199
GABA receptor activation pathway
REACT_75780
G protein gated Potassium channels pathway
REACT_25330
Activation of GABAB receptors pathway
REACT_75918
Inwardly rectifying K+ channels pathway
REACT_75908
Potassium Channels pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_75815
Potassium transport channels pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
KEGG
hsa04971
Gastric acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt Q9Z307
TrEMBL A2A5W7 A2A5W8
UniProt Splice Variant
Entrez Gene 16517
UniGene Mm.30176
RefSeq NM_001252207 NM_001252208 NM_001252209 NM_001252210 NM_010604
OMIM
CCDS CCDS25593
HPRD
IMGT
MGI ID MGI:1314842
MGI Symbol Kcnj16
EMBL AB016197 AK032192 AK045447 AK078905 AK140249 AL592422 AY377989 CH466558
GenPept AAQ88167 BAA34723 BAC27749 BAC32374 BAC37450 BAE24297 CAM17827 EDL34389 EDL34390 EDL34391 EDL34392
RNA Seq Atlas 16517

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca