Homo sapiens Gene: MOK
Summary
InnateDB Gene IDBG-21061.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOK
Gene Name MOK protein kinase
Synonyms RAGE; RAGE-1; RAGE1; STK30
Species Homo sapiens
Ensembl Gene ENSG00000080823
Encoded Proteins
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
MOK protein kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:102224500-102305200
Strand Reverse strand
Band q32.31
Transcripts
ENST00000193029 ENSP00000193029
ENST00000361847 ENSP00000355304
ENST00000521249
ENST00000521766 ENSP00000429348
ENST00000517966 ENSP00000453224
ENST00000523485
ENST00000519569
ENST00000523231 ENSP00000453762
ENST00000524370 ENSP00000452978
ENST00000522874 ENSP00000429469
ENST00000518686
ENST00000522867 ENSP00000454098
ENST00000520266
ENST00000519058 ENSP00000429672
ENST00000524214 ENSP00000428942
ENST00000521937 ENSP00000430416
ENST00000522534 ENSP00000454203
ENST00000522537 ENSP00000453799
ENST00000519477
ENST00000520252
ENST00000524120
ENST00000520046
ENST00000521388 ENSP00000430775
ENST00000521493
ENST00000518399 ENSP00000429570
ENST00000517537 ENSP00000429511
ENST00000522093 ENSP00000429428
ENST00000518482 ENSP00000428206
ENST00000524019
ENST00000519877
ENST00000524207 ENSP00000427884
ENST00000521966
ENST00000520238 ENSP00000428957
ENST00000523169
ENST00000518045
ENST00000559512
ENST00000559138 ENSP00000453401
ENST00000559838 ENSP00000453449
ENST00000557823
ENST00000561150 ENSP00000453950
ENST00000562292 ENSP00000454829
ENST00000619861 ENSP00000482408
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.104119 Hs.614441 Hs.618890 Hs.737935
RefSeq NM_001272011 NM_014226
HUGO
OMIM
CCDS CCDS61552 CCDS9971
HPRD 09310
IMGT
EMBL
GenPept
RNA Seq Atlas