Version 5.4
Mus musculus Gene: Entpd6
Summary
InnateDB Gene IDBG-209357.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Entpd6
Gene Name ectonucleoside triphosphate diphosphohydrolase 6
Synonyms 2700026H11Rik; Cd39l2; NTPDase-6
Species Mus musculus
Ensembl Gene ENSMUSG00000033068
Encoded Proteins
IDBP-209361
ectonucleoside triphosphate diphosphohydrolase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197586:
ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:150749042-150771675
Strand Forward strand
Band G3
Transcripts
ENSMUST00000094467 ENSMUSP00000092038
ENSMUST00000147223
ENSMUST00000146517
ENSMUST00000139723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008894 guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity
GO:0016787 hydrolase activity
GO:0017110 nucleoside-diphosphatase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0008152 metabolic process
GO:0032026 response to magnesium ion
GO:0051592 response to calcium ion
Cellular Component
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197586
View Gene Order
ENSBTAG00000009881
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275524
RefSeq NM_172117 XM_006498643
OMIM
CCDS CCDS16861
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca