Version 5.4
Mus musculus Gene: Cept1
Summary
InnateDB Gene IDBG-184709.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cept1
Gene Name choline/ethanolaminephosphotransferase 1
Synonyms 9930118K05Rik; mCEPT1
Species Mus musculus
Ensembl Gene ENSMUSG00000040774
Encoded Proteins
IDBP-184711
choline/ethanolaminephosphotransferase 1
IDBP-184713
choline/ethanolaminephosphotransferase 1
IDBP-400612
choline/ethanolaminephosphotransferase 1
IDBP-533370
choline/ethanolaminephosphotransferase 1
IDBP-541555
choline/ethanolaminephosphotransferase 1
IDBP-535157
choline/ethanolaminephosphotransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134255:
Cholinephosphotransferase catalyses the final step in the synthesis of phosphatidylcholine by the transfer of phosphocholine from CDP-choline to diacylglycerol. The synthesis of phosphatidylethanolamine by ethanolaminephosphotransferase occurs using an analogous reaction. This gene codes for a choline/ethanolaminephosphotransferase. The protein can synthesize either choline- or ethanolamine- containing phospholipids. Two alternatively spliced transcripts encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:106502260-106547802
Strand Reverse strand
Band F2.3
Transcripts
ENSMUST00000068301 ENSMUSP00000065743
ENSMUST00000039153 ENSMUSP00000037277
ENSMUST00000121231 ENSMUSP00000112509
ENSMUST00000148269 ENSMUSP00000118343
ENSMUST00000137530 ENSMUSP00000115898
ENSMUST00000141525 ENSMUSP00000122460
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004142 diacylglycerol cholinephosphotransferase activity
GO:0004307 ethanolaminephosphotransferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0046872 metal ion binding
Biological Process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006657 CDP-choline pathway
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134255
View Gene Order
ENSBTAG00000020169
Not yet available
Pathways
NETPATH
REACTOME
REACT_199009
Synthesis of PE pathway
REACT_207335
Synthesis of PC pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu00564
Glycerophospholipid metabolism pathway
mmu00565
Ether lipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121238
Synthesis of PC pathway
REACT_120919
Synthesis of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
hsa00565
Ether lipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q8BGS7
TrEMBL D3Z5Y5
UniProt Splice Variant
Entrez Gene 99712
UniGene Mm.486418
RefSeq XM_006502472 NM_133869 XM_006502470
OMIM
CCDS CCDS17723
HPRD
IMGT
MGI ID MGI:2139793
MGI Symbol Cept1
EMBL AC117200 AC140380 AK037116 BC021753 BC023783
GenPept AAH21753 AAH23783 BAC29710
RNA Seq Atlas 99712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca