Version 5.4
Homo sapiens Gene: TM2D2
Summary
InnateDB Gene IDBG-18326.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TM2D2
Gene Name TM2 domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169490
Encoded Proteins
IDBP-236165
TM2 domain containing 2
IDBP-367929
TM2 domain containing 2
IDBP-367935
TM2 domain containing 2
IDBP-479678
TM2 domain containing 2
IDBP-473573
TM2 domain containing 2
IDBP-480299
TM2 domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:38988808-38996824
Strand Reverse strand
Band p11.22
Transcripts
ENST00000397070 ENSP00000380260
ENST00000456397 ENSP00000416050
ENST00000456845 ENSP00000391674
ENST00000522434
ENST00000522142 ENSP00000428394
ENST00000521060
ENST00000524331
ENST00000519186
ENST00000517872 ENSP00000430685
ENST00000520152 ENSP00000428203
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031556
View Gene Order
ENSBTAG00000003516
Not yet available
Cross-References
SwissProt
TrEMBL E5RIT0 E5RJK9
UniProt Splice Variant
Entrez Gene 83877
UniGene Hs.322452 Hs.629585 Hs.7471
RefSeq NM_001024380 NM_001024381 NM_031940 NM_078473 XM_006716408
HUGO HGNC:24127
OMIM 610081
CCDS CCDS43733 CCDS6111
HPRD 16553
IMGT
EMBL AC108863
GenPept
RNA Seq Atlas 83877

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca