Version 5.4
| Mus musculus Gene: Alg12 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-171733.7 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Alg12 | ||||||||
| Gene Name | asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000035845 | ||||||||
| Encoded Proteins |
asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)
asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)
asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182858:
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 15:88805244-88819318 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | E3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
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| KEGG |
N-Glycan biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
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| KEGG |
N-Glycan biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8VDB2 | ||||||||
| TrEMBL | E0CZB5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 223774 | ||||||||
| UniGene | Mm.41512 | ||||||||
| RefSeq | NM_001142357 XM_006520842 NM_145477 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS49694 CCDS27732 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2385025 | ||||||||
| MGI Symbol | Alg12 | ||||||||
| EMBL | AC117700 AJ429133 AK142322 | ||||||||
| GenPept | BAE25031 CAD22101 | ||||||||
| RNA Seq Atlas | 223774 | ||||||||