Version 5.4
Mus musculus Gene: Rnd3
Summary
InnateDB Gene IDBG-169060.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnd3
Gene Name Rho family GTPase 3
Synonyms 2610017M01Rik; AI661404; Arhe; Rhoe
Species Mus musculus
Ensembl Gene ENSMUSG00000017144
Encoded Proteins
IDBP-169062
Rho family GTPase 3
IDBP-626655
Rho family GTPase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115963:
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:51130438-51149111
Strand Reverse strand
Band C1.1
Transcripts
ENSMUST00000017288 ENSMUSP00000017288
ENSMUST00000154545 ENSMUSP00000128831
ENSMUST00000140864
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000115963
View Gene Order
ENSBTAG00000039731
Not yet available
Cross-References
SwissProt P61588
TrEMBL
UniProt Splice Variant
Entrez Gene 74194
UniGene Mm.46497 Mm.468858
RefSeq NM_028810
OMIM
CCDS CCDS16028
HPRD
IMGT
MGI ID MGI:1921444
MGI Symbol Rnd3
EMBL AK011442 AK035195 BC009002
GenPept AAH09002 BAB27622 BAC28975
RNA Seq Atlas 74194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca