Version 5.4
Mus musculus Gene: Irx2
Summary
InnateDB Gene IDBG-165398.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Irx2
Gene Name Iroquois related homeobox 2 (Drosophila)
Synonyms IRX6
Species Mus musculus
Ensembl Gene ENSMUSG00000001504
Encoded Proteins
IDBP-165400
Iroquois related homeobox 2 (Drosophila)
IDBP-626073
Iroquois related homeobox 2 (Drosophila)
IDBP-626076
Iroquois related homeobox 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170561:
IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:72628820-72634198
Strand Forward strand
Band C1
Transcripts
ENSMUST00000074372 ENSMUSP00000073976
ENSMUST00000169028
ENSMUST00000167067 ENSMUSP00000127963
ENSMUST00000163393
ENSMUST00000172353 ENSMUSP00000126691
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001656 metanephros development
GO:0006355 regulation of transcription, DNA-templated
GO:0072086 specification of loop of Henle identity
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000170561
View Gene Order
Cross-References
SwissProt
TrEMBL E9PZB5 V9GXU3
UniProt Splice Variant
Entrez Gene 16372
UniGene Mm.28888 Mm.473067
RefSeq NM_010574 XM_006517110
OMIM
CCDS CCDS26628
HPRD
IMGT
MGI ID MGI:1197526
MGI Symbol Irx2
EMBL CT030229
GenPept
RNA Seq Atlas 16372

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca