Version 5.4
| Mus musculus Gene: Plin2 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-161088.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Plin2 | ||||||||||||||||||||||
| Gene Name | perilipin 2 | ||||||||||||||||||||||
| Synonyms | AA407157; Adfp; ADPH; Adrp | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000028494 | ||||||||||||||||||||||
| Encoded Proteins |
perilipin 2
perilipin 2
perilipin 2
perilipin 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147872:
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 4:86648386-86670060 | ||||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||||
| Band | C4 | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PPARA activates gene expression pathway
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| KEGG | |||||||||||||||||||||||
| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
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| KEGG | |||||||||||||||||||||||
| INOH | |||||||||||||||||||||||
| PID NCI |
HIF-1-alpha transcription factor network
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| Cross-References | |||||||||||||||||||||||
| SwissProt | P43883 | ||||||||||||||||||||||
| TrEMBL | B1AXR3 B1AXR5 Q8C5B5 | ||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | 11520 | ||||||||||||||||||||||
| UniGene | Mm.381 | ||||||||||||||||||||||
| RefSeq | NM_007408 XM_006537557 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS18308 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | MGI:87920 | ||||||||||||||||||||||
| MGI Symbol | Plin2 | ||||||||||||||||||||||
| EMBL | AK078967 AK150177 AK152081 AK152263 AK153222 AK154582 AK167140 AL824707 AY035850 BC054766 L09734 M93275 | ||||||||||||||||||||||
| GenPept | AAA37176 AAH54766 AAK63075 BAC37483 BAE29361 BAE30931 BAE31081 BAE31815 BAE32690 BAE39285 CAM27449 | ||||||||||||||||||||||
| RNA Seq Atlas | 11520 | ||||||||||||||||||||||