InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LPHN2

Summary

InnateDB Protein

IDBP-99897.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LPHN2

Protein Name

latrophilin 2

Synonyms

CIRL2; CL2; LEC1; LPHH1;

Species

Homo sapiens

Ensembl Protein

ENSP00000359762

InnateDB Gene

IDBG-99887 (LPHN2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000203 GPS motif
IPR000832 GPCR, family 2, secretin-like
IPR000922 D-galactoside/L-rhamnose binding SUEL lectin domain
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR003112 Olfactomedin-like
IPR003334 GPCR, family 2, latrophilin, C-terminal
IPR003924 GPCR, family 2, latrophilin
IPR017981 GPCR, family 2-like
IPR022624 Domain of unknown function DUF3497

PFAM