Version 5.4
Homo sapiens Protein: NR4A1
Summary
InnateDB Protein IDBP-718034.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NR4A1
Protein Name
Synonyms GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3;
Species Homo sapiens
Ensembl Protein ENSP00000457070
InnateDB Gene IDBG-33982 (NR4A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 124 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 124 [view]
Protein-Protein 122 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030522 intracellular receptor signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001628 Zinc finger, nuclear hormone receptor-type
IPR003070 Orphan nuclear receptor
IPR003071 Orphan nuclear receptor, HMR type
PFAM PF00105
PRINTS PR00047
PR01284
PR01285
PIRSF
SMART SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BT85
UniProt Splice Variant
Entrez Gene 3164
UniGene Hs.670088
RefSeq
HUGO HGNC:7980
OMIM 139139
CCDS
HPRD 00744
IMGT
EMBL AC025259
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca