Version 5.4
Bos taurus Protein: ALB
Summary
InnateDB Protein IDBP-695510.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALB
Protein Name serum albumin precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022763
InnateDB Gene IDBG-642992 (ALB)
Protein Structure
UniProt Annotation
Function Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Plasma.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 128 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 128 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005504 fatty acid binding
GO:0005515 protein binding
GO:0008144 drug binding
GO:0008289 lipid binding
GO:0015643 toxic substance binding
GO:0019825 oxygen binding
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
GO:0051087 chaperone binding
Biological Process
GO:0001895 retina homeostasis
GO:0006810 transport
GO:0009267 cellular response to starvation
GO:0019836 hemolysis by symbiont of host erythrocytes
GO:0043066 negative regulation of apoptotic process
GO:0051659 maintenance of mitochondrion location
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR000264 ALB/AFP/VDB
IPR001703 Alpha-fetoprotein
IPR014760 Serum albumin, N-terminal
IPR020858 Serum albumin-like
IPR021177 Serum albumin/Alpha-fetoprotein
PFAM PF00273
PRINTS PR00802
PR00803
PIRSF PIRSF002520
SMART SM00103
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P02769
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280717
UniGene Bt.106669
RefSeq NP_851335
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF542068 BC102742 BC142272 M73993 X58989 Y17769
GenPept AAA51411 AAI02743 AAI42273 AAN17824 CAA41735 CAA76847

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca