InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.52974

Summary

InnateDB Protein

IDBP-695289.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.52974

Protein Name

metalloproteinase inhibitor 2 precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000014476

InnateDB Gene

IDBG-642791 (BT.52974)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0008047	enzyme activator activity
GO:0008191	metalloendopeptidase inhibitor activity

Biological Process

GO:0008285	negative regulation of cell proliferation
GO:0010951	negative regulation of endopeptidase activity
GO:0030814	regulation of cAMP metabolic process
GO:0043408	regulation of MAPK cascade
GO:0045664	regulation of neuron differentiation
GO:0071310	cellular response to organic substance

Cellular Component

GO:0005576	extracellular region
GO:0005604	basement membrane
GO:0009986	cell surface
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001134 Netrin domain
IPR001820 Proteinase inhibitor I35, tissue inhibitor of metalloproteinase
IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold

PFAM

PF00965

PRINTS

PIRSF

SMART

SM00206

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite