Version 5.4
| Bos taurus Protein: ARL4D | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Protein | IDBP-692953.2 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | ARL4D | ||||||||||||
| Protein Name | ADP-ribosylation factor-like protein 4D | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Protein | ENSBTAP00000022409 | ||||||||||||
| InnateDB Gene | IDBG-640671 (ARL4D) | ||||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||||
| Function | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form (By similarity). {ECO:0000250}. | ||||||||||||
| Subcellular Localization | Nucleus, nucleolus {ECO:0000250}. Cell membrane. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. | ||||||||||||
| Disease Associations | |||||||||||||
| Tissue Specificity | |||||||||||||
| Comments | |||||||||||||
| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||||
| PDB ID | |||||||||||||
| InterPro |
IPR000795
Elongation factor, GTP-binding domain IPR001806 Small GTPase superfamily IPR003579 Small GTPase superfamily, Rab type IPR005225 Small GTP-binding protein domain IPR006687 Small GTPase superfamily, SAR1-type IPR006689 Small GTPase superfamily, ARF/SAR type IPR006762 Gtr1/RagA G protein IPR013684 Mitochondrial Rho-like IPR019009 Signal recognition particle receptor, beta subunit IPR024156 Small GTPase superfamily, ARF type IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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| PFAM |
PF00009
PF00071 PF00025 PF04670 PF08477 PF09439 |
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| PRINTS |
PR00315
PR00449 PR00328 |
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| PIRSF | |||||||||||||
| SMART |
SM00175
SM00178 SM00177 |
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| TIGRFAMs | |||||||||||||
| Post-translational Modifications | |||||||||||||
| Modification | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | Q0VC18 | ||||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 538936 | ||||||||||||
| UniGene | Bt.62440 | ||||||||||||
| RefSeq | NP_001069603 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | BC120393 | ||||||||||||
| GenPept | AAI20394 | ||||||||||||