InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wdr61

Summary

InnateDB Protein

IDBP-531901.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wdr61

Protein Name

WD repeat domain 61

Synonyms

2700038L12Rik; 2810418I05Rik; REC14;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123077

InnateDB Gene

IDBG-167012 (Wdr61)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
GO:0045638	negative regulation of myeloid cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051571	positive regulation of histone H3-K4 methylation
GO:0080182	histone H3-K4 trimethylation
GO:2001162	positive regulation of histone H3-K79 methylation

Cellular Component

GO:0016593	Cdc73/Paf1 complex
GO:0035327	transcriptionally active chromatin
GO:0055087	Ski complex

Protein Structure and Domains

PDB ID

MGI:1917493

InterPro

IPR001680 WD40 repeat
IPR013979 Translation initiation factor, beta propellor-like domain
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400
PF08662

PRINTS

PR00320

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt