InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DEPDC5

Summary

InnateDB Protein

IDBP-4854.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DEPDC5

Protein Name

DEP domain containing 5

Synonyms

DEP.5; FFEVF;

Species

Homo sapiens

Ensembl Protein

ENSP00000371546

InnateDB Gene

IDBG-4850 (DEPDC5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity

Biological Process

GO:0035556	intracellular signal transduction
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005765	lysosomal membrane
GO:0005829	cytosol
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000591 DEP domain
IPR027244 Vacuolar membrane-associated protein Iml1

PFAM

PF00610
PF12257

PRINTS

PIRSF

SMART

SM00049

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O75140

PhosphoSite

PhosphoSite-O75140

TrEMBL

C9JGS4

UniProt Splice Variant

Entrez Gene

9681

UniGene

RefSeq

NP_001129501

HUGO

HGNC:18423

OMIM

614191

CCDS

CCDS46692

HPRD

16795

IMGT

EMBL

AB014545 AC005004 AJ698950 AJ698951 AJ704764 AK294583 AK294987 AK316364 AL022331 BC057797 BC136612 BC146766 BX640828 CH471095 CR749304 Z82190 Z83856

GenPept

AAD08635 AAH57797 AAI36613 AAI46767 BAA31620 BAG57774 BAG58054 BAH14735 CAE45904 CAG27889 CAG27890 CAG28924 CAH18159 CAI17972 CAI17973 CAI17974 CAI17975 CAI17976 CAI18776 CAI18777 CAI18778 CAI18779 CAI19696 CAI19697 CAI19698 CAI19699 EAW59996