Version 5.4
Homo sapiens Protein: EIF4G1
Summary
InnateDB Protein IDBP-386123.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF4G1
Protein Name eukaryotic translation initiation factor 4 gamma, 1
Synonyms EIF-4G1; EIF4F; EIF4G; EIF4GI; P220; PARK18;
Species Homo sapiens
Ensembl Protein ENSP00000407682
InnateDB Gene IDBG-67809 (EIF4G1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 96 [view]
Protein-Protein 95 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005488 binding
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003307 W2 domain
IPR003890 MIF4G-like, type 3
IPR003891 Initiation factor eIF-4 gamma, MA3
IPR016024 Armadillo-type fold
PFAM PF02020
PF02854
PF02847
PRINTS
PIRSF
SMART SM00515
SM00543
SM00544
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q96I65
UniProt Splice Variant
Entrez Gene 1981
UniGene Hs.605967
RefSeq
HUGO HGNC:3296
OMIM 600495
CCDS
HPRD 06774
IMGT
EMBL AC078797 BC007788 BT007282
GenPept AAH07788 AAP35946

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca