Version 5.4
Homo sapiens Protein: CPEB3
Summary
InnateDB Protein IDBP-382420.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPEB3
Protein Name cytoplasmic polyadenylation element binding protein 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000398310
InnateDB Gene IDBG-82435 (CPEB3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000900 translation repressor activity, nucleic acid binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0008135 translation factor activity, nucleic acid binding
GO:0035613 RNA stem-loop binding
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006412 translation
GO:0007616 long-term memory
GO:0017148 negative regulation of translation
GO:0045727 positive regulation of translation
GO:0048167 regulation of synaptic plasticity
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060998 regulation of dendritic spine development
GO:0060999 positive regulation of dendritic spine development
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0071230 cellular response to amino acid stimulus
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:1900248 negative regulation of cytoplasmic translational elongation
GO:1900365 positive regulation of mRNA polyadenylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030014 CCR4-NOT complex
GO:0030425 dendrite
GO:0043005 neuron projection
GO:0045202 synapse
GO:0097440 apical dendrite
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NE35
PhosphoSite PhosphoSite-Q8NE35
TrEMBL Q5QP71
UniProt Splice Variant
Entrez Gene 22849
UniGene Hs.701732
RefSeq NP_001171608
HUGO HGNC:21746
OMIM 610606
CCDS CCDS53553
HPRD 16745
IMGT
EMBL AB023157 AK302576 AL158040 AL365398 BC036444 CH471066
GenPept AAH36444 BAA76784 BAH13751 CAI13636 CAI14104 EAW50097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca