InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNF641

Summary

InnateDB Protein

IDBP-373873.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNF641

Protein Name

zinc finger protein 641

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000394627

InnateDB Gene

IDBG-30013 (ZNF641)

Protein Structure

UniProt Annotation

Function

Transcriptional activator. Activates transcriptional activities of SRE and AP-1. {ECO:0000269PubMed:16343441}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:16343441}.

Disease Associations

Tissue Specificity

Highly expressed in skeletal muscle, moderate expression in heart, liver, and pancreas, lower expression in placenta, no expression seen in brain, lung, and kidney. {ECO:0000269PubMed:16343441}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter