InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STX10

Summary

InnateDB Protein

IDBP-31905.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STX10

Protein Name

syntaxin 10

Synonyms

hsyn10; SYN10;

Species

Homo sapiens

Ensembl Protein

ENSP00000242770

InnateDB Gene

IDBG-31903 (STX10)

Protein Structure

UniProt Annotation

Function

SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. {ECO:0000269PubMed:18195106}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed at high levels in heart, skeletal muscle and pancreas.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0016192	vesicle-mediated transport
GO:0048193	Golgi vesicle transport

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000727 Target SNARE coiled-coil domain
IPR010989 t-SNARE
IPR015260 Syntaxin 6, N-terminal

PFAM

PF05739
PF09177

PRINTS

PIRSF

SMART

SM00397

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-O60499

TrEMBL

X6R2W0

UniProt Splice Variant

Entrez Gene

8677

UniGene

RefSeq

NP_001258538

HUGO

HGNC:11428

OMIM

603765

CCDS

CCDS62570

HPRD

04791

IMGT

EMBL

AC011446

GenPept