Version 5.4
Mus musculus Protein: Diablo
Summary
InnateDB Protein IDBP-257800.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Diablo
Protein Name diablo homolog (Drosophila)
Synonyms 0610041G12Rik; 1700006L01Rik; AU040403; Smac;
Species Mus musculus
Ensembl Protein ENSMUSP00000107213
InnateDB Gene IDBG-199693 (Diablo)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0051402 neuron apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
Protein Structure and Domains
PDB ID MGI:1913843
InterPro IPR009062 Smac/DIABLO-like
IPR015142 Smac/DIABLO protein
PFAM PF09057
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z2Q3
UniProt Splice Variant
Entrez Gene 66593
UniGene Mm.46716
RefSeq
MGI ID
MGI Symbol Diablo
OMIM
CCDS
HPRD
IMGT
EMBL AC157931
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca