Version 5.4
Mus musculus Protein: Ckmt1
Summary
InnateDB Protein IDBP-202171.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ckmt1
Protein Name creatine kinase, mitochondrial 1, ubiquitous
Synonyms mi-CK; Mt-CK; ScCKmit; UbCKmit;
Species Mus musculus
Ensembl Protein ENSMUSP00000000317
InnateDB Gene IDBG-202167 (Ckmt1)
Protein Structure
UniProt Annotation
Function Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Subcellular Localization Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004111 creatine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0016310 phosphorylation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Protein Structure and Domains
PDB ID MGI:99441
InterPro IPR022413 ATP:guanido phosphotransferase, N-terminal
IPR022414 ATP:guanido phosphotransferase, catalytic domain
PFAM PF02807
PF00217
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P30275
PhosphoSite PhosphoSite-P30275
TrEMBL Q545N7
UniProt Splice Variant
Entrez Gene 12716
UniGene Mm.252145
RefSeq NP_034027
MGI ID
MGI Symbol Ckmt1
OMIM
CCDS CCDS16640
HPRD
IMGT
EMBL AK005076 AK131953 AL845466 BC025976 CH466519 Z13968 Z13969
GenPept AAH25976 BAB23800 BAE20897 CAA78371 CAA78372 EDL28049

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca