InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acta1

Summary

InnateDB Protein

IDBP-199781.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acta1

Protein Name

actin, alpha 1, skeletal muscle

Synonyms

AA959943; Acta-2; Acts; Actsk-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034453

InnateDB Gene

IDBG-199779 (Acta1)

Protein Structure

UniProt Annotation

Function

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Subcellular Localization

Cytoplasm, cytoskeleton.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.

Experimentally validated
Total	20 [view]
Protein-Protein	18 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	79 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0009612	response to mechanical stimulus
GO:0009991	response to extracellular stimulus
GO:0010226	response to lithium ion
GO:0016049	cell growth
GO:0030240	skeletal muscle thin filament assembly
GO:0043503	skeletal muscle fiber adaptation
GO:0048545	response to steroid hormone
GO:0048741	skeletal muscle fiber development

Cellular Component

GO:0001725	stress fiber
GO:0005615	extracellular space
GO:0005865	striated muscle thin filament
GO:0005884	actin filament
GO:0015629	actin cytoskeleton
GO:0030017	sarcomere
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle