InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Alb

Summary

InnateDB Protein

IDBP-178484.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Alb

Protein Name

albumin

Synonyms

Alb-1; Alb1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031314

InnateDB Gene

IDBG-178482 (Alb)

Protein Structure

UniProt Annotation

Function

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Plasma.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 137 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	23 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	137 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005504	fatty acid binding
GO:0005515	protein binding
GO:0008144	drug binding
GO:0008270	zinc ion binding
GO:0015643	toxic substance binding
GO:0019825	oxygen binding
GO:0019899	enzyme binding
GO:0030170	pyridoxal phosphate binding
GO:0051087	chaperone binding

Biological Process

GO:0001895	retina homeostasis
GO:0006810	transport
GO:0007584	response to nutrient
GO:0009267	cellular response to starvation
GO:0010033	response to organic substance
GO:0019836	hemolysis by symbiont of host erythrocytes
GO:0043066	negative regulation of apoptotic process
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046689	response to mercury ion
GO:0051659	maintenance of mitochondrion location
GO:0070541	response to platinum ion

Cellular Component

GO:0005576	extracellular region
GO:0005604	basement membrane
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle