Version 5.4
| Mus musculus Protein: Nubp2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-149553.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Nubp2 | ||||||||||
| Protein Name | nucleotide binding protein 2 | ||||||||||
| Synonyms | D17Wsu11e; | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Protein | ENSMUSP00000049319 | ||||||||||
| InnateDB Gene | IDBG-149551 (Nubp2) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. {ECO:0000255HAMAP-Rule:MF_03039}. | ||||||||||
| Subcellular Localization | Nucleus {ECO:0000255HAMAP-Rule:MF_03039, ECO:0000269PubMed:16638812}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255HAMAP-Rule:MF_03039, ECO:0000269PubMed:16638812}. Note=Enriched at the centrosomes during mitosis. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Widely expressed. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | MGI:1347072 | ||||||||||
| InterPro |
IPR002586
CobQ/CobB/MinD/ParA nucleotide binding domain IPR005129 ArgK protein IPR015223 ATPase MipZ/NubP2/Cfd1 IPR019591 ATPase-like, ParA/MinD IPR025723 Anion-transporting ATPase-like domain IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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| PFAM |
PF01656
PF03308 PF09140 PF10609 PF02374 |
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| PRINTS | |||||||||||
| PIRSF | |||||||||||
| SMART | |||||||||||
| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q9R061 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 26426 | ||||||||||
| UniGene | Mm.36718 | ||||||||||
| RefSeq | NP_036086 | ||||||||||
| MGI ID | |||||||||||
| MGI Symbol | Nubp2 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS28500 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AF114169 AK003816 BC012635 | ||||||||||
| GenPept | AAF01785 AAH12635 BAB23013 | ||||||||||