Version 5.4
Homo sapiens Gene: ZC4H2
Summary
InnateDB Gene IDBG-73225.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZC4H2
Gene Name zinc finger, C4H2 domain containing
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000126970
Encoded Proteins
IDBP-73227
zinc finger, C4H2 domain containing
IDBP-73229
zinc finger, C4H2 domain containing
IDBP-374263
zinc finger, C4H2 domain containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:64915802-65034713
Strand Reverse strand
Band q11.2
Transcripts
ENST00000374839 ENSP00000363972
ENST00000337990 ENSP00000338650
ENST00000447788 ENSP00000399126
ENST00000488608
ENST00000488406
ENST00000492653
ENST00000488831
ENST00000476032
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0007399 nervous system development
GO:0007528 neuromuscular junction development
GO:0021522 spinal cord motor neuron differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035062
View Gene Order
ENSBTAG00000003779
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.28249 Hs.739472
RefSeq NM_001178032 NM_001178033 NM_001243804 NM_018684
HUGO
OMIM
CCDS CCDS14380 CCDS55431 CCDS55432
HPRD 06584
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca