Version 5.4
Homo sapiens Gene: ARL4D
Summary
InnateDB Gene IDBG-52781.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARL4D
Gene Name ADP-ribosylation factor-like 4D
Synonyms ARF4L; ARL6
Species Homo sapiens
Ensembl Gene ENSG00000175906
Encoded Proteins
IDBP-52783
ADP-ribosylation factor-like 4D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking. Mutations in this gene have been associated with Bardet-Biedl syndrome (BBS). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:43398959-43401137
Strand Forward strand
Band q21.31
Transcripts
ENST00000320033 ENSP00000322628
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0009306 protein secretion
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034936
View Gene Order
ENSBTAG00000016847
Not yet available
Cross-References
SwissProt P49703
TrEMBL
UniProt Splice Variant
Entrez Gene 379
UniGene Hs.183153
RefSeq NM_001661
HUGO HGNC:656
OMIM 600732
CCDS CCDS11463
HPRD
IMGT
EMBL AB060692 AK314951 BC000043 CH471178 L38490 U25771
GenPept AAA57126 AAA93229 AAH00043 BAB91080 BAG37456 EAW51681 EAW51682
RNA Seq Atlas 379

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca