Version 5.4
Homo sapiens Gene: HAUS3
Summary
InnateDB Gene IDBG-233647.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS3
Gene Name HAUS augmin-like complex, subunit 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000214367
Encoded Proteins
IDBP-7367
HAUS augmin-like complex, subunit 3
IDBP-360990
HAUS augmin-like complex, subunit 3
IDBP-485088
HAUS augmin-like complex, subunit 3
IDBP-484510
HAUS augmin-like complex, subunit 3
IDBP-481368
HAUS augmin-like complex, subunit 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary HAUS3 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:2227464-2242164
Strand Reverse strand
Band p16.3
Transcripts
ENST00000243706 ENSP00000243706
ENST00000443786 ENSP00000392903
ENST00000506763 ENSP00000427350
ENST00000514395 ENSP00000423285
ENST00000502440 ENSP00000427356
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005874 microtubule
GO:0070652 HAUS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000079555
View Gene Order
ENSBTAG00000024787
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.665869
RefSeq NM_024511
HUGO
OMIM
CCDS CCDS33941
HPRD 10784
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca