Version 5.4
Mus musculus Gene: Capn5
Summary
InnateDB Gene IDBG-200226.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Capn5
Gene Name calpain 5
Synonyms nCL-3
Species Mus musculus
Ensembl Gene ENSMUSG00000035547
Encoded Proteins
IDBP-200228
calpain 5
IDBP-267366
calpain 5
IDBP-541022
calpain 5
IDBP-540600
calpain 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the calpain family of proteins. Unlike many members of the calpain gene family, this gene lacks a calmodulin-like domain, required for calcium binding. Mouse models for Huntington\'s disease displayed increased levels of the protein encoded by this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:98121559-98178274
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000040971 ENSMUSP00000048183
ENSMUST00000107112 ENSMUSP00000102729
ENSMUST00000134638
ENSMUST00000155056 ENSMUSP00000116697
ENSMUST00000129430 ENSMUSP00000121200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0009986 cell surface
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149260
View Gene Order
ENSBTAG00000005034
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.326847
RefSeq NM_007602 XM_006507275 XM_006507276 XM_006507277
OMIM
CCDS CCDS21465
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca