Version 5.4
Mus musculus Gene: Rdh11
Summary
InnateDB Gene IDBG-152796.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rdh11
Gene Name retinol dehydrogenase 11
Synonyms 2610319N22Rik; AI428145; Arsdr1; AU045252; C85936; CGI-82; HCBP12; M42C60; Mdt1; Psdr1; SCALD; Ube-1c; UBE-1c1
Species Mus musculus
Ensembl Gene ENSMUSG00000066441
Encoded Proteins
IDBP-152798
retinol dehydrogenase 11
IDBP-540144
retinol dehydrogenase 11
IDBP-538247
retinol dehydrogenase 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072042:
The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:79174337-79192293
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000085254 ENSMUSP00000082352
ENSMUST00000161204 ENSMUSP00000124066
ENSMUST00000159500 ENSMUSP00000123829
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004745 retinol dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0050662 coenzyme binding
GO:0052650 NADP-retinol dehydrogenase activity
Biological Process
GO:0008152 metabolic process
GO:0016062 adaptation of rhodopsin mediated signaling
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0044237 cellular metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0001917 photoreceptor inner segment
GO:0005622 intracellular
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000072042
View Gene Order
ENSBTAG00000001950
Not yet available
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_198569
Retinoid metabolism and transport pathway
REACT_188277
The canonical retinoid cycle in rods (twilight vision) pathway
REACT_188260
Visual phototransduction pathway
REACT_188257
Signal Transduction pathway
REACT_188255
Diseases associated with visual transduction pathway
KEGG
mmu00830
Retinol metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160156
The canonical retinoid cycle in rods (twilight vision) pathway
REACT_24968
Retinoid metabolism and transport pathway
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_160125
Visual phototransduction pathway
REACT_116125
Disease pathway
KEGG
hsa00830
Retinol metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.473084 Mm.489533
RefSeq NM_021557
OMIM
CCDS CCDS36480
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca